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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NR2C1 All Species: 7.88
Human Site: T362 Identified Species: 14.44
UniProt: P13056 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13056 NP_001027458.1 603 67315 T362 G D S S I N Y T E K E G P L L
Chimpanzee Pan troglodytes XP_001137621 678 75113 T437 G D S S I N Y T E K E G P L L
Rhesus Macaque Macaca mulatta XP_001107297 554 61731 G319 F Q E M Q T N G D V S R A F D
Dog Lupus familis XP_854792 605 67422 Y363 A G D S S I N Y I E K E G P L
Cat Felis silvestris
Mouse Mus musculus Q505F1 590 65487 P354 S F V E K E G P L L S E S H V
Rat Rattus norvegicus Q8VIJ4 590 65509 P354 S C M E R E G P L L S D S H V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510105 561 61971 L326 I V E I E G P L L S D A H V A
Chicken Gallus gallus O42101 501 57084 L266 A S I P H L I L E L Q K C E P
Frog Xenopus laevis Q66J63 637 70793 V396 N L L P D V N V E I E G P L L
Zebra Danio Brachydanio rerio Q06725 411 45463 S176 L N G H C Y L S G Y I S L L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P16375 543 57969 L308 G F N G H S Y L S S Y I S L L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9N4B8 615 68010 Y355 Q N P R N H Q Y I S E I T T R
Sea Urchin Strong. purpuratus Q26622 583 63834 M347 P M L S D H H M Q F K L T T P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.2 90.3 96 N.A. 87.5 87.5 N.A. 77.7 21.5 72.6 27 N.A. 22 N.A. 22.9 49
Protein Similarity: 100 87.6 91.2 97.6 N.A. 92.2 91.7 N.A. 84.7 40.9 82.7 42.7 N.A. 37.8 N.A. 42.1 65.1
P-Site Identity: 100 100 0 13.3 N.A. 0 0 N.A. 0 6.6 40 13.3 N.A. 26.6 N.A. 6.6 6.6
P-Site Similarity: 100 100 6.6 26.6 N.A. 6.6 6.6 N.A. 13.3 13.3 40 26.6 N.A. 40 N.A. 20 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 0 0 0 0 0 0 0 0 0 8 8 0 8 % A
% Cys: 0 8 0 0 8 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 16 8 0 16 0 0 0 8 0 8 8 0 0 8 % D
% Glu: 0 0 16 16 8 16 0 0 31 8 31 16 0 8 0 % E
% Phe: 8 16 0 0 0 0 0 0 0 8 0 0 0 8 0 % F
% Gly: 24 8 8 8 0 8 16 8 8 0 0 24 8 0 0 % G
% His: 0 0 0 8 16 16 8 0 0 0 0 0 8 16 0 % H
% Ile: 8 0 8 8 16 8 8 0 16 8 8 16 0 0 0 % I
% Lys: 0 0 0 0 8 0 0 0 0 16 16 8 0 0 0 % K
% Leu: 8 8 16 0 0 8 8 24 24 24 0 8 8 39 47 % L
% Met: 0 8 8 8 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 8 16 8 0 8 16 24 0 0 0 0 0 0 0 0 % N
% Pro: 8 0 8 16 0 0 8 16 0 0 0 0 24 8 16 % P
% Gln: 8 8 0 0 8 0 8 0 8 0 8 0 0 0 0 % Q
% Arg: 0 0 0 8 8 0 0 0 0 0 0 8 0 0 8 % R
% Ser: 16 8 16 31 8 8 0 8 8 24 24 8 24 0 0 % S
% Thr: 0 0 0 0 0 8 0 16 0 0 0 0 16 16 0 % T
% Val: 0 8 8 0 0 8 0 8 0 8 0 0 0 8 16 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 24 16 0 8 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _